A chemist can produce water in his laboratory by mixing hydrogen and oxygen, but he is in fact acting under the direction of the Supreme Lord, besides the elements he manipulates are also supplied to him by Him. As such, God knows everything directly as well as indirectly. He knows all things in their finest details and He always remains perfectly independent. It is compared to a gold mine, and the various cosmic creations, in their myriad forms, galaxies, to items made from this gold. The gold of various objects, rings, necklaces, etc., shares the same properties as the gold of the mine, qualitatively is one with it, but differs in quantity. This is why it is affirmed of the Absolute Truth that It is simultaneously different and not different from all that is. Nothing is absolutely equal to Absolute Truth, but at the same time everything depends on it.
Conditioned souls, from Brahma, the first created being and ruler of the galaxy in which we live, to the tiny ant, are engaged without exception in the creative act, but none are independent of the Supreme Lord. The materialist mistakenly believes that he is no other creator than himself. This is called maya, the illusion. Because of his meager knowledge, he cannot see beyond what his imperfect senses allow him to perceive, and he thus comes to believe that matter forms itself, without the aid of a superior intelligence. The Complete Whole, the Absolute Truth, being the source of all that exists, nothing is independent of Him. Every action and reaction of each embodied body is automatically known to the Whole, Krishna. Likewise, if the entire creation represents the body of the Absolute All, the Absolute has direct and indirect knowledge of everything. No one except the Supreme Being, God, is fully aware of everything and perfectly independent. Everyone must acquire knowledge from a superior teacher. The Lord, in his total perfection, looks at matter and thus creates living beings, which are an integral part of his Person. They are indeed so many spiritual sparks with which He permeates the vast material creation. It is then that the creative energies are set in motion to generate so many wonders. All must obey Him wholeheartedly, and whoever aspires to break the slavery of matter must surrender to Him.
Unless you surrender yourself to the Supreme Lord, you are sure to fall into delusion, even if you are a great thinker. Only when a great spirit surrenders to God and fully recognizes Him as the cause of all causes, can it become a great soul with a truly broad mind. Such souls are very rare, but only great souls can know the Supreme Lord, the Absolute, the root cause of all creation. It is called the Ultimate Truth, because all other truths are relative to Him, and He remains free from the illusion that takes hold of anyone who knows only the relative.
Lord Chaitanya gives this advice:
Always read Srimad-Bhagavatam and seek to understand each verse. You will then grasp the true meaning of Brahma-Sutra or Vedanta-Sutra [Great philosophical treatise of Avatar Vyasadeva, made up of aphorisms, succinct formulas containing a deep teaching, in particular on the nature of Absolute Truth, Krishna]. You say that you are very keen to study Vedanta-Sutra, but you cannot understand it without a correct understanding of Srimad-Bhagavatam, Words of wisdom.